Dr. Jason Fung may be the top expert in using intermittent, alternate day, and long term fasting to combat diabetes and obesity.
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————————————– Key Timestamps———————————-
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04:03 The Calories notion is false.
13:54 We have a mechanism in our body that determines how fat we get.
19:39 Your body weight set point is being reset upward.
20:23 To reset your body weight set point, you need to get your insulin low for a significant amount of time in order to get your leptin levels low.
24:14 When you eat all day, you are telling your body to store fat all day and you get fat.
25:07 Fat storage is a hormonal signal, not a caloric signal.
29:41 Intermittent fasting is not about how many calories you eat. It is about the time that you are not eating.
31:24 Insulin inhibits lipolysis, stopping you from burning fat.
32:24 On a 7 day water only fast, your insulin falls and you switch from burning food to burning fat.
33:13 During fasting, as your insulin falls, you get a counter-regulatory hormone surge, increasing adrenaline, noradrenaline, growth hormone and cortisol.
33:53 There is a period of gluconeogenesis at around 24 hours into fasting. You will burn protein, not muscle.
35:40 If the old protein is never broken down, you cannot build new protein.
37:26 You get much better retention of lean mass with an intermittent fasting strategy over cutting calories.
38:24 Biggest Loser style diets sink metabolic rates.
42:15 Women can fast. Ghrelin is the hunger hormone. Women have higher ghrelin spikes.
43:01 If you don't eat over 24 hours ghrelin spikes 3 times, at breakfast, lunch and dinner, then drops. Hunger does not continue to increase.
45:04 Cravings disappear with fasting and keto.
49:38 You can eat high carb foods and keep low insulin.
51:09 Sugar is more fattening than other carbohydrates.
53:51 Natural foods have natural satiety mechanisms.
01:08:31 Type 2 diabetes is misunderstood by doctors.
01:10:08 Blood glucose is a symptom of type 2 diabetes. We treat the symptom, not the disease.
01:12:15 Type 2 diabetes is reversible, except for the very late stage.
01:16:42 The longer you've been overweight the more it effects weight loss.
01:18:08 There are conflicts of interest in medicine. Much evidence is produced by pharmaceutical companies. Universities take funding from industry and produce shoddy research.
01:30:21 Bias in nutrition science is rampant and has stymied the advancement of actual science. Special interest needs to be out of research.